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Within our study, we had been capable of drastically escalate the dose of CX-5461 outside of that reached in the initial-in-human analyze in people with hematologic cancers. The RP2D of 475 mg/m2 on times 1, 8, and 15 of the four-week cycle, was based on phototoxicity, which transpired Inspite of rigorous UV light avoidance protocols and within t